Название
C(sp2)-Thio- and amino-methylated indole derivatives: one-pot synthesis, evaluation of cytotoxic and anti-inflammatory activity
Авторы
Akhmetova V.R., Leont’ev D.V., Akhmadiev N.S., Perfilova V.N., Sirotenko V.S., Paramonov E.A., Prokofiev I.I., Sagalaev M.A., Khairullina V.R., Ishmetova D.V., Vakhitova Y.V.
Базы цитирования
Scopus, Web of Science, Ядро РИНЦ, SCImago, РИНЦ, Белый список
Scopus ID
2-s2.0-10504122268
Статус ВолгГМУ
Проверен
Ключевые слова
aminothiols; anti-inflammatory activity; cytotoxic activity; formaldehyde; indole; one-pot synthesis; 12 (carboxymethyl) 3,4,5,6 tetrahydro 1h [1,4,6] thiadiazocino [4 3 a] indole 4 acetate pyridine; 12 [(dimethylamino)methyl] 3,4,5,6 tetrahydro 1h [1,4,6] thiadiazocino [4 3 a] indole 4 acetate pyridine; 1h indol 3 yl methyl aminoethylsulfonic acid; 2 (3,4,5,6 tetrahydro 1h [1,4,6] thiadiazocino [4 3 a] indol 12 yl) acetate pyridine; antiinflammatory agent; arachidonic acid; cyclooxygenase 1; cyclooxygenase 2; cytotoxic agent; diclofenac; indole derivative; indometacin; nimesulide; unclassified drug; A-549 cell line; animal experiment; animal model; antiinflammatory activity; Article; cell membrane; comparative study; controlled study; cytotoxicity; experimental osteoarthritis; HCT 116 cell line; HEK293-A cell line; Hep-G2 cell line; human; human cell; hydrophilicity; in vivo study; Jurkat cell line; lipophilicity; MCF-7 cell line; metabolic clearance; molecular docking; nonhuman; nuclear magnetic resonance; one pot synthesis; proton nuclear magnetic resonance; rat; THP-1 cell line
Год
2026
Журнал
Medicinal Chemistry Research
Язык
Английский
Направления исследований
3.4.2. Фармацевтическая химия, фармакогнозия, 1.4.3. Органическая химия
Том
35
Стр. начала
1330
Стр. окончания
1340
Кол. страниц
11
Публикация, изданная за рубежом
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